Health Benefits of Lion's Mane
is a type of medicinal mushroom. Long used in traditional Chinese
medicine, lion's mane is widely available in supplement form.
Scientific research shows that lion's mane contains a number of
health-promoting substances, including antioxidants and beta-glucan.
claim that lion's mane can help with a variety of health problems,
addition, lion's mane is said to strengthen the immune system,
stimulate digestion, and protect against cancer.
from animal-based research, test-tube studies, and small clinical
trials indicate that lion's mane may offer certain health benefits,
including support for neuronal health.
a look at some key study findings.
mane may benefit older adults with mild cognitive impairment,
according to a small study published in Phytotherapy
2009. For the study, researchers assigned 30 older adults with mild
cognitive impairment to take either lion's mane extract or a placebo
day for 16 weeks. In cognitive tests given at weeks eight, 12, and 16
of the study, members of the lion's mane group showed significantly
greater improvements compared to members of the placebo group.
a more recent study (published in Biomedical
2011), scientists examined the effects of lion's mane on brain
function in mice. Results revealed that lion's mane helped protect
against memory problems caused by the buildup of amyloid beta (a
substance that forms the brain plaques associated with Alzheimer's
have also shown a possible neuro-protective effect against ischemic
National Center for Complementary and Integrative Health (NCCIH)
cautions that while some small preliminary studies on the impact of
natural supplements on cognitive function have shown modest effects,
"direct evidence is lacking." Claims made to the contrary
are not supported by evidence
mane may help alleviate depression and anxiety, suggests a small
study published in Biomedical
2010. For the study, 30 menopausal women consumed cookies containing
either lion's mane or a placebo every day for four weeks. Analyzing
study findings, researchers observed that members of the lion's mane
group were less irritable and anxious and had less difficulty
concentrating than members of the placebo group.
research suggests that lion's mane shows promise in protection
against cancer. For instance, in a 2011 study published in Food
tests on human cells revealed that lion's mane may help knock out
addition, a 2011 study published in the Journal
of Agricultural and Food Chemistry found
that lion's mane extract helped reduce the size of cancerous colon
tumors in mice.
study's findings suggest that lion's mane may help fight off colon
cancer, in part by increasing activity in certain cells involved in
the immune response. Another study found that the extract might help
reduce the spread of colon cancer cells to the lungs.
it's too soon to tell whether lion's mane can help prevent or reduce
cancer in humans.
is known about the safety of long-term use and side effects of lion's
there's some concern that lion's mane may aggravate symptoms in
people with allergies and asthma. Therefore, it's important to
consult your physician prior to using lion's mane, or any other
supplement, if you have a history of allergies and/or asthma or any
other medical condition.
mane is commonly consumed in many Asian countries for medicinal and
culinary purposes. However, recommended dosage for various benefits
is unknown due to a lack of studies.
women should avoid using lion's mane products as insufficient
evidence is available to determine if any dosage is safe during
lion's mane supplements have been marketed with unsupported claims,
such as the promotion of weight loss, brain health, and the
prevention of heart disease.
example, in 2019, the Food and Drug Administration (FDA) sent a
warning letter to Pure Nootropics, LLC, for making unsubstantiated
claims about a variety of their products, including for their lion's
mane powder. The company was marketing the supplement as "great
for brain injury recovery" and to "reduce symptoms of
anxiety and depression." Since then, the company has removed
these specific claims from their marketing but continue to claim that
the product "supports overall cognitive health.
Mane Mushroom: Benefits, Side Effects, Dosage, and Interactions